レビュー： デング

 Dengue
The Lancet, Early Online Publication, 14 September 2014
doi:10.1016/S0140-6736(14)60572-9

エボラ熱定義（EU)

Ebola virus disease case definition for reporting in EU
http://www.ecdc.europa.eu/en/healthtopics/ebola_marburg_fevers/EVDcasedefinition/Pages/default.aspx

Clinical criteria

Any person currently presenting or having presented before death:

• Fever ≥38.6°C

AND any of the following:

• Severe headache
• Vomiting, diarrhoea, abdominal pain
• Unexplained haemorrhagic manifestations in various forms
• Multi-organ failure

OR a person who died suddenly and inexplicably

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Laboratory criteria

Any of the following:

• Detection of Ebola virus nucleic acid in a clinical specimen and confirmation by sequencing or a second assay on different genomic targets.
• Isolation of Ebola virus from a clinical specimen.

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Epidemiological criteria

In the 21 days before the onset of symptoms:

• having been in an affected area;

OR

• having had contact with a probable or confirmed EVD case.

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High-risk exposure criteria

Any of the following:

• close face-to-face contact (e.g. within one metre) without appropriate personal protective equipment (including eye protection) with a probable or confirmed case who was coughing, vomiting, bleeding, or who had diarrhoea; or had unprotected sexual contact with a case up to three months after recovery;
• direct contact with any material soiled by bodily fluids from a probable or confirmed case;
• percutaneous injury (e.g. with needle) or mucosal exposure to bodily fluids, tissues or laboratory specimens of a probable or confirmed case;
• participation in funeral rites with direct exposure to human remains in or from an affected area without appropriate personal protective equipment;
• direct contact with bats, rodents, primates, living or dead, in or from affected areas, or bushmeat.

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