気管支拡張について、リウマチ関連、COPD合併の2つを主に評価
[Bronchiectasis Rheumatoid overlap syndrome (BROS) is an independent risk factor for mortality in patients with bronchiectasis: A multicentre cohort study
Anthony De Soyza, et. al.
Chest. 2017. doi:10.1016/j.chest.2016.12.024
Bronchiectasis Severity Index (BSI)
以下分類
- BROS (those with RA and Bronchiectasis without interstitial lung disease)
- idiopathic bronchiectasis,
- Bronchiectasis-COPD overlap syndrome (BCOS)
- “other” BR aetiologies
欧州6センター・コホート、 1716名のBSI評価例
BROS 147例(コホート8.5%)
BROSと死亡率に相関、気管支拡張急性増悪率、気管支拡張関連入院とは相関認めず
- 平均48ヶ月間の死亡率は、特発性BR 9.3%、他要因BR 8.6%
- RAでは 18%、BCOSでは 28.5%
BROS、BCOSでは、他病因気管支拡張に比べ死亡率効率
BSIスコアは特発性BRに比べ、BROSで統計学的に増加するも、臨床的意義少ない
(BSI mean 7.7 vs. 7.1 , p < 0.05)
BCOSはBSIスコア有意に高く (mean 10.4)、緑膿菌コロナイゼーション率高く (24%)、入院既往多い (58%)
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Radiological severity of bronchiectasis was assessed using a modified Reiff score, which assesses the number of lobes involved (with the lingula considered to be a separate lobe) and the degree of dilatation (tubular = 1, varicose = 2, and cystic = 3). The maximum score is 18 and minimum score is 1.
びまん性汎細気管支炎、副鼻腔気管支症候群に関しては?