中間部位プロアドレノメジュリン（MR‐ProAM）:COPD予後因子

中間部位プロアドレノメジュリン（MR‐ProAM）はCOPD急性増悪、市中肺炎入院患者で増加。COPD患者の予後推定として役立つかも。


Stable-State Midrange-Proadrenomedullin Level Is a Strong Predictor of Mortality in Patients With COPD
Maaike C. et. al.
Chest. 2014;145(3):534-541. doi:10.1378/chest.13-106

	MR-proADM, mean ± SD, nmol/L		PCT, median (IQR), ng/mL
	Stable State	Exacerbation	Stable State	Exacerbation
Nonsurvivors (n = 78)	0.94 ± 0.41	1.08 ± 0.50	0.06 (0.04-0.09)	0.08 (0.04-0.19)
Survivors (n = 103)	0.72 ± 0.25	0.78 ± 0.27	0.05 (0.03-0.06)	0.05 (0.03-0.09)
Difference between groups, P value	< .001	< .001	< .001	0.005