内科開業医のお勉強日記: 日照の乏しいところは卒中リスク増加

2012年2月4日土曜日

日照の乏しいところは卒中リスク増加

REGARDS (Reasons for Geographic and Racial Differences in Stroke)研究
American Stroke Association's International Stroke Conference でのスピーチ発表

1万6千名を越える黒人・白人で、日照の乏しい地域では56％の卒中リスク増加

http://newsroom.heart.org/pr/aha/wednesday-stroke-news-tips-221529.aspx

3 p.m. CT – Abstract 2591

Lack of sunlight may increase stroke risk

A new study found that people who lived in areas with the least sunlight during the year had the highest risk of stroke.

After adjustment for other risk factors, those who experienced sunlight exposure below the median had a 1.6 higher risk of stroke. Extreme temperatures also were linked to an increased stroke risk.

Researchers obtained data from 16,606 participants in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study. The participants were interviewed by phone, in-home evaluations and a self-administered questionnaire for residential histories since birth.

Researchers merged a 15-year residential history with satellite and ground monitor data to determine sunlight and temperature exposure.

They used 15-, 10-, five-, two- and one-year exposures to predict stroke incidence. Over an average of five years of follow-up, 351 participants had a stroke.

The study is the first to show an association between sunlight and stroke. Researchers also confirmed the results of other studies that linked cold temperatures to an increased risk of stroke.

Future research may reveal whether the finding stands and whether it’s due to short- or long-term exposure, researchers said.

This study was funded by the National Institutes of Health/National Institute of Neurologic Disorders and Stroke.

Note: Actual presentation is 6:15 p.m. CT, Wednesday, Feb. 1, 2012.

大気汚染などの共役要素除外が十分でないという問題点も挙げられている。

ビタミンD研究とからみ、卒中・認知症リスク減少効果の報告とからみ、この結果を考察している。

都道府県レベルだし、虚血性卒中など病型無視、もちろん背景因子無視だからおおざっぱすぎだが・・・一応並べてみた

日本国内・都道府県での年間日照時間