NIPPON DATA80:心電図・時計回りは死亡リスク・心不全リスクと関連、反時計回りは・・・

Epidemiology and Prevention
Prognostic Values of Clockwise and Counterclockwise Rotation for Cardiovascular Mortality in Japanese Subjects
A 24-Year Follow-Up of the National Integrated Project for Prospective Observation of Noncommunicable Disease and Its Trends in the Aged, 1980–2004 (NIPPON DATA80)

Yasuyuki Nakamura, et. al.

Circulation. 2012; 125: 1226-1233 Published online before print February 3, 2012, doi: 10.1161/​CIRCULATIONAHA.111.070045 


Coxモデルを用いた多変量補正ハザード比（HR)では、生化学的所見・他のECG所見を含む検討で、


時計回り回転は有意に、両性での、心不全と正の相関 　(HR=1.79; 95% confidence interval [CI], 1.13–2.83; P=0.013)、男性と両性においてCVD  (HR=1.49; 95% CI, 1.12–1.98; P=0.007 in men; HR=1.28; 95% CI, 1.02–1.59; P=0.030 in combined)と相関、両性の総死亡率と相関　 (HR=1.19; 95% CI, 1.00–1.49; P=0.0496 in men; HR=1.15; 95% CI, 1.00–1.32; P=0.045 in combined)

反時計回り回転は、両性で、卒中と逆相関 　 (HR=0.77; 95% CI, 0.62–0.96; P=0.017), CVD in men and in men and women combined (HR=0.74; 95% CI, 0.59–0.94; P=0.011 in men; HR=0.81; 95% CI, 0.70–0.94; P=0.006 in combined)、女性において卒中と逆相関 (HR=0.87; 95% CI, 0.77–0.98; P=0.023)

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時計回りの意義は左心系への負荷を表し分かる気がするが、反時計回転の意義が分からない。
でも、フルテキスト入手するほどの意欲はわかない・・・